Alphabetic Index FY2027

I68.0

Cerebral amyloid angiopathy

FY2027Chapter 9: Diseases of the circulatory system/I60–I69 Cerebrovascular diseases

BillableComplete code, valid to report
Care settingsHospice: not accepted as primary

I68.0 (also written I680) is a billable ICD-10-CM diagnosis code for cerebral amyloid angiopathy. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 3 codes in category I68 (Cerebrovascular disorders in diseases classified elsewhere). The Alphabetic Index lists it under 2 entries. Its coding notes include a Code first instruction, a Use additional code instruction, 1 Excludes1 entry and 10 Excludes2 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

This code
  • underlying amyloidosis (E85.-)

Use additional code

Add the listed code as a secondary code, if known.

Also from chapter/block level (8 notes)
Inherited from I60–I69 Cerebrovascular diseases
  • code to identify presence of:
    • alcohol abuse and dependence (F10.-)
    • exposure to environmental tobacco smoke (Z77.22)
    • history of tobacco dependence (Z87.891)
    • hypertension (I10-I1A)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Also from chapter/block level (1 note)
Inherited from I60–I69 Cerebrovascular diseases
  • traumatic intracranial hemorrhage (S06.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (10 notes)
Inherited from Chapter 9 Diseases of the circulatory system
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • transient cerebral ischemic attacks and related syndromes (G45.-)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospice: not accepted as primary

Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Manifestation code. Report the underlying condition first (see the Code first note).

Source: CMS Integrated Outpatient Code Editor (IOCE) v27.3, effective October 1, 2026, edit 86

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries