G72.2

Myopathy due to other toxic agents

FY2027Chapter 6: Diseases of the nervous system/G70–G73 Diseases of myoneural junction and muscle

BillableComplete code, valid to report

G72.2 (also written G722) is a billable ICD-10-CM diagnosis code for myopathy due to other toxic agents. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 9 codes in category G72 (Other and unspecified myopathies). The Alphabetic Index lists it under 2 entries. Its coding notes include a Code first instruction, 5 Excludes1 entries and 8 Excludes2 entries.

Code first

If the underlying condition listed here is present and known, sequence it first.

This code

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from G72 Other and unspecified myopathies
  • arthrogryposis multiplex congenita (Q74.3)
  • dermatopolymyositis (M33.-)
  • ischemic infarction of muscle (M62.2-)
  • myositis (M60.-)
  • polymyositis (M33.2.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (8 notes)
Inherited from Chapter 6 Diseases of the nervous system
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

IRF 60% Rule

On the CMS list of diagnoses used to determine presumptive compliance with the IRF 60 percent rule.

Source: CMS IRF Presumptive Compliance-3, FY 2027 IRF PPS final rule files, effective for discharges on or after October 1, 2026

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 45 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries