F32.3
Major depressive disorder, single episode, severe with psychotic features
F32.3 (also written F323) is a billable ICD-10-CM diagnosis code for major depressive disorder, single episode, severe with psychotic features. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 10 codes in category F32 (Depressive episode). The Alphabetic Index lists it under 10 entries. Its coding notes include 3 Excludes1 entries and 2 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (1 note)
- symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Home Health Primary
Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the Behavioral Health clinical group.
Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026Hospital CC
Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 12 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CIPF Primary
IPF MS-DRG adjustment. A principal diagnosis of this code groups to this MS-DRG:
| MS-DRG | Description | Factor |
|---|---|---|
| 885 | Psychoses | 1.00 |
Includes
Further defines or gives examples of the content of the category.
- single episode of agitated depression
- single episode of depressive reaction
- single episode of major depression
- single episode of psychogenic depression
- single episode of reactive depression
- single episode of vital depression
Also from chapter/block level (1 note)
- disorders of psychological development
Inclusion terms
Conditions classified to this code.
- Single episode of major depression with mood-congruent psychotic symptoms
- Single episode of major depression with mood-incongruent psychotic symptoms
- Single episode of major depression with psychotic symptoms
- Single episode of psychogenic depressive psychosis
- Single episode of psychotic depression
- Single episode of reactive depressive psychosis
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 10 entries
- Depression (acute) (mental), major, with psychotic symptoms
- Depression (acute) (mental), psychotic (single episode)
- Depression (acute) (mental), reactive (psychogenic) (single episode), psychotic (single episode)
- Disorder (of), depressive, major, single episode, severe (without psychotic symptoms), with psychotic symptoms
- Disorder (of), depressive, major, with psychotic symptoms
- Episode, depressive, major, severe (without psychotic symptoms), with psychotic symptoms
- Melancholia, reactive (emotional stress or trauma)
- Psychosis, psychotic, psychogenic (paranoid), depressive
- Psychosis, psychotic, reactive (brief) (transient) (emotional stress) (psychological trauma), depressive
- Reaction, depressive (single episode), psychotic