F05
Delirium due to known physiological condition
F05 is a billable ICD-10-CM diagnosis code for delirium due to known physiological condition. It is part of the FY2027 code set, effective October 1, 2026. The Alphabetic Index lists it under 26 entries. Its coding notes include a Code first instruction, 1 Excludes1 entry and 2 Excludes2 entries.
Code first
If the underlying condition listed here is present and known, sequence it first.
- the underlying physiological condition, such as:
- dementia (F03.9-)
Excludes1
Not coded here. The listed conditions generally should not be reported together.
- delirium NOS (R41.0)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (1 note)
- symptoms, signs and abnormal clinical laboratory findings, not elsewhere classified (R00-R99)
Care settings
How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.
Hospice: not accepted as primary
Not accepted as the principal diagnosis on a hospice claim (bill types 081x and 082x). The Integrated OCE returns an edit for this code.
Reason: Supplementary or additional code, not allowed as principal diagnosis.
Hospital CC
Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 1 code in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.
Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix CIPF Primary
IPF MS-DRG adjustment. A principal diagnosis of this code groups to this MS-DRG:
| MS-DRG | Description | Factor |
|---|---|---|
| 880 | Acute adjustment reaction & psychosocial dysfunction | 1.08 |
Includes
Further defines or gives examples of the content of the category.
Also from chapter/block level (1 note)
- disorders of psychological development
Inclusion terms
Conditions classified to this code.
- Acute or subacute brain syndrome
- Acute or subacute confusional state (nonalcoholic)
- Acute or subacute infective psychosis
- Acute or subacute organic reaction
- Acute or subacute psycho-organic syndrome
- Delirium of mixed etiology
- Delirium superimposed on dementia
- Sundowning
Notes
Also from chapter/block level (1 note)
- This block comprises a range of mental disorders grouped together on the basis of their having in common a demonstrable etiology in cerebral disease, brain injury, or other insult leading to cerebral dysfunction. The dysfunction may be primary, as in diseases, injuries, and insults that affect the brain directly and selectively; or secondary, as in systemic diseases and disorders that attack the brain only as one of the multiple organs or systems of the body that are involved.
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 26 entries
- Confusion, confused, acute, with dementia
- Confusion, confused, epileptic
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), due to (secondary to), general medical condition
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), due to (secondary to), multiple etiologies
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), postprocedural (postoperative)
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), puerperal
- Delirium, delirious (acute or subacute) (not alcohol- or drug-induced), with, dementia
- Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety), with, acute confusional state
- Epilepsy, epileptic, epilepsia (attack) (cerebral) (convulsion) (fit) (seizure), twilight
- Insanity, insane, confusional, acute or subacute
- Psychosis, psychotic, confusional, acute or subacute
- Psychosis, psychotic, infective (acute) (subacute)
Show 14 more
- Psychosis, psychotic, organic, due to or associated with, disease, endocrine or metabolic, acute or subacute
- Psychosis, psychotic, organic, due to or associated with, epilepsy transient (acute)
- Psychosis, psychotic, organic, due to or associated with, infection, brain (intracranial), acute or subacute
- Psychosis, psychotic, organic, due to or associated with, trauma, brain (birth) (from electric current) (surgical), acute or subacute
- Psychosis, psychotic, organic, infective, acute or subacute
- Psychosis, psychotic, organic, post-traumatic, acute or subacute
- Puerperal, puerperium (complicated by, complications), delirium NEC
- Senile, senility, with, acute confusional state
- State (of), confusional (psychogenic), acute, with, senility or dementia
- State (of), confusional (psychogenic), epileptic
- State (of), twilight, epileptic
- Sundowning
- Syndrome, psycho-organic (nonpsychotic severity), acute or subacute
- Twilight state, epileptic