E07.81

Sick-euthyroid syndrome

FY2027Chapter 4: Endocrine, nutritional and metabolic diseases/E00–E07 Disorders of thyroid gland

BillableComplete code, valid to report

E07.81 (also written E0781) is a billable ICD-10-CM diagnosis code for sick-euthyroid syndrome. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 5 codes in category E07 (Other disorders of thyroid). The Alphabetic Index lists it under 2 entries. Its coding notes include 1 Excludes1 entry.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Also from chapter/block level (1 note)
Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Endocrine clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

IPF Primary

IPF MS-DRG adjustment. A principal diagnosis of this code groups to one of these MS-DRGs. Which one depends on other facts of the stay, so the factor is a range:

MS-DRGDescriptionFactor
947Signs and Symptoms w MCC1.12
948Signs and Symptoms w/out MCC1.09
A principal diagnosis that groups to none of the 19 designated MS-DRGs gets no MS-DRG adjustment. Otherwise the claim still receives the federal per diem base rate and the other adjustments.

Source: CMS IPF PPS FY 2027 final rule (CMS-1847-F), Addendum A; code lists from the CMS MS-DRG Definitions Manual v44; effective for discharges on or after October 1, 2026

Inclusion terms

Conditions classified to this code.

This code
  • Euthyroid sick-syndrome

Notes

Also from chapter/block level (1 note)
Inherited from Chapter 4 Endocrine, nutritional and metabolic diseases
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 2 entries