D68.5
Primary thrombophilia
Non-billable headerNot valid on its own. Use one of the more specific codes under it.
D68.5 is a non-billable ICD-10-CM code header for primary thrombophilia. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D68.51 Activated protein C resistance, D68.52 Prothrombin gene mutation and D68.59 Other primary thrombophilia. Its coding notes include 10 Excludes1 entries and 11 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
This code
- antiphospholipid syndrome (D68.61)
- lupus anticoagulant (D68.62)
- secondary activated protein C resistance (D68.69)
- secondary antiphospholipid antibody syndrome (D68.69)
- secondary lupus anticoagulant with hypercoagulable state (D68.69)
- secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)
- systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
- systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)
- thrombotic thrombocytopenic purpura (M31.19)
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Inherited from D68 Other coagulation defects
Also from chapter/block level (9 notes)
Inherited from Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Inclusion terms
Conditions classified to this code.
This code
- Primary hypercoagulable states