D38.0

Neoplasm of uncertain behavior of larynx

FY2027Chapter 2: Neoplasms/D37–D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

BillableComplete code, valid to report

D38.0 (also written D380) is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of larynx. It is part of the FY2027 code set, effective October 1, 2026. It is one of the 7 codes in category D38 (Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs). Its coding notes include 5 Excludes1 entries.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold NOS (D37.05)
  • neoplasm of uncertain behavior of hypopharyngeal aspect of aryepiglottic fold (D37.05)
  • neoplasm of uncertain behavior of marginal zone of aryepiglottic fold (D37.05)
Inherited from D38 Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs
  • neoplasm of uncertain behavior of heart (D48.7)
Also from chapter/block level (1 note)
Inherited from D37–D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
  • neoplasms of unspecified behavior (D49.-)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Home Health Primary

Accepted as the primary (principal) diagnosis on a home health claim. The Home Health Grouper assigns it to the MMTA - Infectious Disease, Neoplasms, and Blood-Forming Diseases clinical group.

Source: CMS Home Health Grouper Software v07.2.26, effective October 1, 2026

IPF Comorbidity

On the CMS IPF comorbidity list.

Comorbidity categoryFactor
Oncology Treatment1.44
It counts as a comorbidity when reported as a secondary diagnosis and actively treated during the stay. An IPF receives only one adjustment within a category and can receive adjustments in more than one category.

Source: CMS IPF PPS FY 2027 final rule (CMS-1847-F), Addendum B-3 (comorbidity codes with adjustment factor); effective for discharges on or after October 1, 2026

Inclusion terms

Conditions classified to this code.

This code
  • Neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold, laryngeal aspect
  • Neoplasm of uncertain behavior of epiglottis (suprahyoid portion)

Notes

Also from chapter/block level (9 notes)
Inherited from D37–D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
  • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
Inherited from Chapter 2 Neoplasms
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).