B03

Smallpox

FY2027Chapter 1: Certain infectious and parasitic diseases/B00–B09 Viral infections characterized by skin and mucous membrane lesions

BillableComplete code, valid to report
Care settingsHospital CC

B03 is a billable ICD-10-CM diagnosis code for smallpox. It is part of the FY2027 code set, effective October 1, 2026. The Alphabetic Index lists it under 4 entries. Its coding notes include a Use additional code instruction and 5 Excludes2 entries.

Use additional code

Add the listed code as a secondary code, if known.

Also from chapter/block level (1 note)
Inherited from Chapter 1 Certain infectious and parasitic diseases
  • code to identify resistance to antimicrobial drugs (Z16.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (5 notes)
Inherited from Chapter 1 Certain infectious and parasitic diseases
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Care settings

How CMS programs treat this code. These are CMS claim edits and list entries, not coverage or eligibility rules.

Hospital CC

Counts as a complication or comorbidity (CC) when reported as a secondary diagnosis on an inpatient claim. It does not count when the principal diagnosis is one of the 13 codes in its exclusion list. Some MS-DRGs also ignore a CC or MCC that defines the DRG.

Source: CMS MS-DRG Definitions Manual v44, effective October 1, 2026, Appendix C

Includes

Further defines or gives examples of the content of the category.

Also from chapter/block level (1 note)
Inherited from Chapter 1 Certain infectious and parasitic diseases
  • diseases generally recognized as communicable or transmissible

Notes

This code
  • In 1980 the 33rd World Health Assembly declared that smallpox had been eradicated.
  • The classification is maintained for surveillance purposes.

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 4 entries