A41.5
Sepsis due to other Gram-negative organisms
A41.5 is a non-billable ICD-10-CM code header for sepsis due to other Gram-negative organisms. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are A41.50 Gram-negative sepsis, unspecified; A41.51 Sepsis due to Escherichia coli [E. coli]; A41.52 Sepsis due to Pseudomonas; A41.53 Sepsis due to Serratia and 2 more. Its coding notes include a Code first instruction, a Use additional code instruction, 4 Excludes1 entries and 18 Excludes2 entries.
Guidelines tip
From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.
Sepsis is coded to the underlying systemic infection, with A41.9 as the default. Urosepsis has no default code and the provider must be queried. R65.2 needs documented severe sepsis or associated organ dysfunction.
Code first
If the underlying condition listed here is present and known, sequence it first.
- , if applicable, postprocedural sepsis (T81.44-)
- sepsis due to central venous catheter (T80.211-)
- sepsis during labor (O75.3)
- sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82)
- sepsis following immunization (T88.0-)
- sepsis following infusion, transfusion or therapeutic injection (T80.22-, T80.29-)
Use additional code
Add the listed code as a secondary code, if known.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- sepsis (due to) (in) actinomycotic (A42.7)
- sepsis (due to) (in) anthrax (A22.7)
- sepsis (due to) (in) candidal (B37.7)
- sepsis (due to) (in) Erysipelothrix (A26.7)
- sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
- sepsis (due to) (in) gonococcal (A54.86)
- sepsis (due to) (in) herpesviral (B00.7)
- sepsis (due to) (in) listerial (A32.7)
- sepsis (due to) (in) melioidosis (A24.1)
- sepsis (due to) (in) meningococcal (A39.2-A39.4)
- sepsis (due to) (in) plague (A20.7)
- sepsis (due to) (in) tularemia (A21.7)
- toxic shock syndrome (A48.3)
Also from chapter/block level (5 notes)
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Includes
Further defines or gives examples of the content of the category.
Also from chapter/block level (1 note)
- diseases generally recognized as communicable or transmissible