A41

Other sepsis

FY2027Chapter 1: Certain infectious and parasitic diseases/A30–A49 Other bacterial diseases

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

Code first
Use additional code
Excludes1
Excludes2

A41 is a non-billable ICD-10-CM code category for other sepsis. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are A41.0 Sepsis due to Staphylococcus aureus, A41.1 Sepsis due to other specified staphylococcus, A41.2 Sepsis due to unspecified staphylococcus, A41.3 Sepsis due to Hemophilus influenzae and 4 more. Its coding notes include a Code first instruction, a Use additional code instruction, 4 Excludes1 entries and 18 Excludes2 entries.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

Sepsis is coded to the underlying systemic infection, with A41.9 as the default. Urosepsis has no default code and the provider must be queried. R65.2 needs documented severe sepsis or associated organ dysfunction.

Guidelines I.C.1.d.1.aSepsis, severe sepsis and urosepsisRead the official text

Code first

If the underlying condition listed here is present and known, sequence it first.

This code

, if applicable, postprocedural sepsis (T81.44-)
sepsis due to central venous catheter (T80.211-)
sepsis during labor (O75.3)
sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82)
sepsis following immunization (T88.0-)
sepsis following infusion, transfusion or therapeutic injection (T80.22-, T80.29-)

Use additional code

Add the listed code as a secondary code, if known.

Also from chapter/block level (1 note)

Inherited from Chapter 1 Certain infectious and parasitic diseases

code to identify resistance to antimicrobial drugs (Z16.-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code

bacteremia NOS (R78.81)
neonatal (P36.-)
puerperal sepsis (O85)
streptococcal sepsis (A40.-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

This code

sepsis (due to) (in) actinomycotic (A42.7)
sepsis (due to) (in) anthrax (A22.7)
sepsis (due to) (in) candidal (B37.7)
sepsis (due to) (in) Erysipelothrix (A26.7)
sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
sepsis (due to) (in) gonococcal (A54.86)
sepsis (due to) (in) herpesviral (B00.7)
sepsis (due to) (in) listerial (A32.7)
sepsis (due to) (in) melioidosis (A24.1)
sepsis (due to) (in) meningococcal (A39.2-A39.4)
sepsis (due to) (in) plague (A20.7)
sepsis (due to) (in) tularemia (A21.7)
toxic shock syndrome (A48.3)

Also from chapter/block level (5 notes)

Inherited from Chapter 1 Certain infectious and parasitic diseases

carrier or suspected carrier of infectious disease (Z22.-)
certain localized infections - see body system-related chapters
infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
infectious and parasitic diseases specific to the perinatal period (P35-P39)
influenza and other acute respiratory infections (J00-J22)

Includes

Further defines or gives examples of the content of the category.

Also from chapter/block level (1 note)

Inherited from Chapter 1 Certain infectious and parasitic diseases

diseases generally recognized as communicable or transmissible

Alphabetic Index terms

Terms the official Alphabetic Index lists for this code. 1 entry

Disorder (of), glomerular (in), sepsis NEC

More specific codes under A41 8