I22

Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

FY2027Chapter 9: Diseases of the circulatory system/I20–I25 Ischemic heart diseases

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

I22 is a non-billable ICD-10-CM code category for subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are I22.0 Subsequent ST elevation (STEMI) myocardial infarction of anterior wall, I22.1 Subsequent ST elevation (STEMI) myocardial infarction of inferior wall, I22.2 Subsequent non-ST elevation (NSTEMI) myocardial infarction, I22.8 Subsequent ST elevation (STEMI) myocardial infarction of other sites and 1 more. Its coding notes include a Use additional code instruction, a Code also instruction, 2 Excludes1 entries and 10 Excludes2 entries.

Guidelines tip

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

I22 is only for a subsequent MI when both the initial and the subsequent MI are type 1 or unspecified. Subsequent type 2, 4 or 5 MIs have their own I21.A codes.

Guidelines I.C.9.e.4Subsequent acute myocardial infarctionRead the official text

Use additional code

Add the listed code as a secondary code, if known.

This code
  • code, if applicable, to identify:
    • exposure to environmental tobacco smoke (Z77.22)
    • history of tobacco dependence (Z87.891)
    • occupational exposure to environmental tobacco smoke (Z57.31)
    • status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)
    • tobacco dependence (F17.-)
    • tobacco use (Z72.0)

Code also

Two codes may be needed to describe the condition. This note gives no sequencing order.

Also from chapter/block level (1 note)
Inherited from I20–I25 Ischemic heart diseases
  • the presence of hypertension (I10-I1A)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • subsequent myocardial infarction, type 2 (I21.A1)
  • subsequent myocardial infarction of other type (type 3) (type 4) (type 5) (I21.A9)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Also from chapter/block level (10 notes)
Inherited from Chapter 9 Diseases of the circulatory system
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • transient cerebral ischemic attacks and related syndromes (G45.-)

Includes

Further defines or gives examples of the content of the category.

This code
  • acute myocardial infarction occurring within four weeks (28 days) of a previous acute myocardial infarction, regardless of site
  • cardiac infarction
  • coronary (artery) embolism
  • coronary (artery) occlusion
  • coronary (artery) rupture
  • coronary (artery) thrombosis
  • infarction of heart, myocardium, or ventricle
  • recurrent myocardial infarction
  • reinfarction of myocardium
  • rupture of heart, myocardium, or ventricle
  • subsequent type 1 myocardial infarction

More specific codes under I22 5