D80
Immunodeficiency with predominantly antibody defects
D80 is a non-billable ICD-10-CM code category for immunodeficiency with predominantly antibody defects. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D80.0 Hereditary hypogammaglobulinemia, D80.1 Nonfamilial hypogammaglobulinemia, D80.2 Selective deficiency of immunoglobulin A [IgA], D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses and 6 more. Its coding notes include 2 Excludes1 entries and 10 Excludes2 entries.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
Also from chapter/block level (10 notes)
- human immunodeficiency virus [HIV] disease (B20)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Includes
Further defines or gives examples of the content of the category.
Also from chapter/block level (3 notes)
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
More specific codes under D80 10
- D80.0Hereditary hypogammaglobulinemiaBillable
- D80.1Nonfamilial hypogammaglobulinemiaBillable
- D80.2Selective deficiency of immunoglobulin A [IgA]Billable
- D80.3Selective deficiency of immunoglobulin G [IgG] subclassesBillable
- D80.4Selective deficiency of immunoglobulin M [IgM]Billable
- D80.5Immunodeficiency with increased immunoglobulin M [IgM]Billable
- D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemiaBillable
- D80.7Transient hypogammaglobulinemia of infancyBillable
- D80.8Other immunodeficiencies with predominantly antibody defectsBillable
- D80.9Immunodeficiency with predominantly antibody defects, unspecifiedBillable