Alphabetic Index FY2027

T80.31

ABO incompatibility with hemolytic transfusion reaction

FY2027Chapter 19: Injury, poisoning and certain other consequences of external causes/T80–T88 Complications of surgical and medical care, not elsewhere classified

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

T80.31 is a non-billable ICD-10-CM code header for ABO incompatibility with hemolytic transfusion reaction. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are T80.310 ABO incompatibility with acute hemolytic transfusion reaction; T80.311 ABO incompatibility with delayed hemolytic transfusion reaction and T80.319 ABO incompatibility with hemolytic transfusion reaction, unspecified. Its coding notes include a Use additional code instruction, 1 Excludes1 entry and 30 Excludes2 entries.

7th characters

Every code below needs one of these (defined at T80).

The appropriate 7th character is to be added to each code from category T80

  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela

Guidelines tips

From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.

The 7th character depends on whether the patient is in active treatment, not on who sees the patient. An aftercare Z code is not used for injury aftercare.

Guidelines I.C.19.aInjuries: application of 7th charactersRead the official text

A complication code needs the provider's documented cause-and-effect link between the care and the condition. Some T codes already include the type of procedure, so no external cause code is needed.

Guidelines I.B.16; I.C.19.g.4Complications of careRead the official text

Use additional code

Add the listed code as a secondary code, if known.

Also from chapter/block level (4 notes)
Inherited from T80–T88 Complications of surgical and medical care, not elsewhere classified
  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • code(s) to identify the specified condition resulting from the complication
  • code to identify devices involved and details of circumstances (Y62-Y82)
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • code to identify any retained foreign body, if applicable (Z18.-)

Excludes1

Not coded here. The listed conditions generally should not be reported together.

Inherited from T80.3 ABO incompatibility reaction due to transfusion of blood or blood products
  • minor blood group antigens reactions (Duffy) (E) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S) (T80.A-)

Excludes2

Not included here. Both codes may be reported if the patient has both conditions.

Inherited from T80 Complications following infusion, transfusion and therapeutic injection
  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)
Also from chapter/block level (23 notes)
Inherited from T80–T88 Complications of surgical and medical care, not elsewhere classified
  • any encounters with medical care for postprocedural conditions in which no complications are present, such as:
    • artificial opening status (Z93.-)
    • closure of external stoma (Z43.-)
    • fitting and adjustment of external prosthetic device (Z44.-)
    • burns and corrosions from local applications and irradiation (T20-T32)
    • complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
    • mechanical complication of respirator [ventilator] (J95.850)
    • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
    • postprocedural fever (R50.82)
  • specified complications classified elsewhere, such as:
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Includes

Further defines or gives examples of the content of the category.

Inherited from T80 Complications following infusion, transfusion and therapeutic injection
  • complications following perfusion

Notes

Also from chapter/block level (2 notes)
Inherited from Chapter 19 Injury, poisoning and certain other consequences of external causes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

More specific codes under T80.31 3