Guidelines › Encounters for chemotherapy, immunotherapy and radiation therapy

Encounters for chemotherapy, immunotherapy and radiation therapy

Official text from the FY2027 ICD-10-CM Official Guidelines for Coding and Reporting. The wording is quoted exactly.

Guidelines I.C.2.e.2

“assign code Z51.0, Encounter for antineoplastic radiation therapy, or Z51.11, Encounter for antineoplastic chemotherapy, or Z51.12, Encounter for antineoplastic immunotherapy as the first-listed or principal diagnosis.”

“The malignancy for which the therapy is being administered should be assigned as a secondary diagnosis.”

“If a patient admission/encounter is for the insertion or implantation of radioactive elements (e.g., brachytherapy) the appropriate code for the malignancy is sequenced as the principal or first-listed diagnosis. Code Z51.0 should not be assigned.”

Where this applies

3 billable codes. Source: FY 2027 ICD-10-CM Official Guidelines for Coding and Reporting, effective October 1, 2026. Full Guidelines (PDF, CMS)

The Guidelines are the authority for assigning codes, and following them is required under HIPAA. This page quotes them for convenience and is not a substitute for the official document. See the Terms and Disclaimer.