Alphabetic Index FY2027

D21

Other benign neoplasms of connective and other soft tissue

FY2027Chapter 2: Neoplasms/D10–D36 Benign neoplasms, except benign neuroendocrine tumors

Non-billable headerNot valid on its own. Use one of the more specific codes under it.

D21 is a non-billable ICD-10-CM code category for other benign neoplasms of connective and other soft tissue. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are D21.0 Benign neoplasm of connective and other soft tissue of head, face and neck; D21.1 Benign neoplasm of connective and other soft tissue of upper limb, including shoulder; D21.2 Benign neoplasm of connective and other soft tissue of lower limb, including hip; D21.3 Benign neoplasm of connective and other soft tissue of thorax and 4 more. Its coding notes include 13 Excludes1 entries.

Excludes1

Not coded here. The listed conditions generally should not be reported together.

This code
  • benign neoplasm of articular cartilage (D16.-)
  • benign neoplasm of cartilage of larynx (D14.1)
  • benign neoplasm of cartilage of nose (D14.0)
  • benign neoplasm of connective tissue of breast (D24.-)
  • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
  • benign neoplasm of peritoneum (D20.1)
  • benign neoplasm of retroperitoneum (D20.0)
  • benign neoplasm of uterine ligament, any (D28.2)
  • benign neoplasm of vascular tissue (D18.-)
  • hemangioma (D18.0-)
  • lipomatous neoplasm (D17.-)
  • lymphangioma (D18.1)
  • uterine leiomyoma (D25.-)

Includes

Further defines or gives examples of the content of the category.

This code
  • benign neoplasm of blood vessel
  • benign neoplasm of bursa
  • benign neoplasm of cartilage
  • benign neoplasm of fascia
  • benign neoplasm of fat
  • benign neoplasm of ligament, except uterine
  • benign neoplasm of lymphatic channel
  • benign neoplasm of muscle
  • benign neoplasm of synovia
  • benign neoplasm of tendon (sheath)
  • benign stromal tumors

Notes

Also from chapter/block level (8 notes)
Inherited from Chapter 2 Neoplasms
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

More specific codes under D21 8