C49.A
Gastrointestinal stromal tumor
C49.A is a non-billable ICD-10-CM code header for gastrointestinal stromal tumor. Report a more specific code from it instead. It is part of the FY2027 code set, effective October 1, 2026. The more specific codes under it are C49.A0 Gastrointestinal stromal tumor, unspecified site; C49.A1 Gastrointestinal stromal tumor of esophagus; C49.A2 Gastrointestinal stromal tumor of stomach; C49.A3 Gastrointestinal stromal tumor of small intestine and 3 more. Its coding notes include 5 Excludes1 entries and 7 Excludes2 entries.
Guidelines tip
From the FY2027 Official Guidelines. ICD10Ref adds no rules of its own.
A primary malignancy code stays in use until treatment directed at that site is completed. After that, with no evidence of disease at the site, Z85 gives the former site.
Excludes1
Not coded here. The listed conditions generally should not be reported together.
Excludes2
Not included here. Both codes may be reported if the patient has both conditions.
- Kaposi's sarcoma of soft tissue (C46.1)
- malignant neoplasm of heart (C38.0)
- malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
- malignant neoplasm of peritoneum (C48.2)
- malignant neoplasm of retroperitoneum (C48.0)
- malignant neoplasm of uterine ligament (C57.3)
- mesothelioma (C45.-)
Includes
Further defines or gives examples of the content of the category.
- malignant neoplasm of blood vessel
- malignant neoplasm of bursa
- malignant neoplasm of cartilage
- malignant neoplasm of fascia
- malignant neoplasm of fat
- malignant neoplasm of ligament, except uterine
- malignant neoplasm of lymphatic vessel
- malignant neoplasm of muscle
- malignant neoplasm of synovia
- malignant neoplasm of tendon (sheath)
Notes
Also from chapter/block level (8 notes)
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Alphabetic Index terms
Terms the official Alphabetic Index lists for this code. 1 entry
More specific codes under C49.A 7
- C49.A0Gastrointestinal stromal tumor, unspecified siteBillable
- C49.A1Gastrointestinal stromal tumor of esophagusBillable
- C49.A2Gastrointestinal stromal tumor of stomachBillable
- C49.A3Gastrointestinal stromal tumor of small intestineBillable
- C49.A4Gastrointestinal stromal tumor of large intestineBillable
- C49.A5Gastrointestinal stromal tumor of rectumBillable
- C49.A9Gastrointestinal stromal tumor of other sitesBillable